When administering diclofenac sodium to a patient with chronic bursitis, what action should the nurse take?

Giving diclofenac sodium with food is advisable to minimize gastrointestinal irritation, which is a common side effect of non-steroidal anti-inflammatory drugs (NSAIDs). Since diclofenac can cause stomach discomfort and even complications like ulcers or gastritis, taking it with food can help buffer the stomach lining and reduce the risk of these adverse effects. In the context of a patient with chronic bursitis, managing pain while protecting the gastrointestinal tract is crucial for effective treatment.

Administering the medication on an empty stomach could increase the likelihood of gastrointestinal side effects. Applying a cool compress before administration might provide temporary relief but doesn't directly relate to the medication administration process itself, nor does it address the need for food to mitigate side effects. Monitoring vital signs before administering is typically important for other medications but is not specifically required or influenced by the administration of diclofenac. Thus, taking diclofenac sodium with food is the best practice for patient safety and comfort.