What side effect is haloperidol most commonly associated with?

Haloperidol, an antipsychotic medication, is most commonly associated with extrapyramidal symptoms (EPS) due to its mechanism of action. As a typical antipsychotic, it primarily works by blocking dopamine receptors in the brain, particularly D2 receptors. This inhibition can disrupt normal motor control, leading to various movement disorders. EPS can include symptoms such as tremors, rigidity, bradykinesia, and tardive dyskinesia, which are all related to alterations in the basal ganglia's functioning.

These side effects are significant because they can profoundly impact a patient's quality of life and may deter adherence to treatment. Therefore, recognizing these potential complications is crucial for healthcare providers to monitor and manage patients adequately while they are on haloperidol.

In contrast, the other side effects listed are less commonly associated with haloperidol specifically. Cardiac arrhythmias can occur, especially with other medications or electrolyte imbalances but are not the primary concern. Skin rash and excessive sweating are also possible side effects of various medications but are not the hallmark issues linked with haloperidol.