What is a common side effect of antidepressants?

Weight gain is recognized as a common side effect of many antidepressants, particularly those in the selective serotonin reuptake inhibitor (SSRI) and tricyclic antidepressant (TCA) classes. These medications can influence metabolism, appetite, and energy expenditure, potentially leading to increased body weight over time. It's essential for healthcare providers to monitor patients for changes in weight and to discuss lifestyle strategies to mitigate this effect when prescribing these medications.

While some patients might experience increased energy levels, enhanced sleep quality, or improved appetite as they respond positively to treatment, these outcomes are not universally applicable and can vary greatly among individuals. In contrast, the tendency for certain antidepressants to lead to weight gain is a well-documented concern that often prompts discussions about medication choices and lifestyle modifications.