What are potential side effects of calcium channel blockers?

Calcium channel blockers are a class of medications primarily used to manage hypertension and certain heart conditions. They work by inhibiting calcium ions from entering cells of the heart and blood vessel walls, resulting in relaxed muscles and dilation of blood vessels. While effective, they also have a range of potential side effects.

Peripheral edema can occur due to the vasodilatory effects of these medications, which can lead to fluid accumulation in the lower extremities. Constipation is another common side effect because calcium channel blockers can decrease gastrointestinal motility by affecting smooth muscle. Lastly, hypotension may arise because of their ability to lower blood pressure by reducing vascular resistance.

These specific side effects—peripheral edema, constipation, and hypotension—are well-known by healthcare providers and can guide them in monitoring patients and modifying treatment if necessary. Being aware of these potential adverse effects can help in managing and anticipating patient responses to therapy with calcium channel blockers.